Common Disease: Are Causative Alleles Common or Rare?
نویسندگان
چکیده
منابع مشابه
Common Disease: Are Causative Alleles Common or Rare?
It has been said that a week is a long time in politics. But in human disease gene mapping, 10 years can seem a very short time indeed. It once seemed so simple: find a family with a number of affected individuals and narrow down regions of the genome shared by affected individuals but not their unaffected siblings. This process (family linkage analysis) was lengthy but had notable success with...
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ژورنال
عنوان ژورنال: PLoS Biology
سال: 2011
ISSN: 1545-7885
DOI: 10.1371/journal.pbio.1001009